General Cell Based Assays
AURORA BIOLABS LLC Kras Q61R Nucleotide Exchange Assay Kit,100 rxn
KRAS is a small GTPase in the RAS protein family that plays a critical role in regulating cell signaling pathways involved in proliferation, differentiation, and survival. KRAS cycles between an inactive GDP-bound state and an active GTP-bound state, and activation occurs through nucleotide exchange from GDP to GTP. Mutations such as KRAS Q61R are frequently associated with human cancers and contribute to abnormal signaling and uncontrolled cell growth. The KRAS Q61R Nucleotide Exchange Assay is a TR-FRET–based assay designed to quantitatively monitor nucleotide exchange activity of KRAS Q61R. The assay detects changes in fluorescence resonance energy transfer generated during nucleotide exchange, enabling measurement of KRAS activation and evaluation of compounds that modulate KRAS signaling for cancer research and drug discovery applications.
Revvity Health Sciences Inc HTRF Human Phospho-STAT5 (Tyr694) Detection Kit, 500 Assay Points
HTRF Human Phospho-STAT5 (Tyr694) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Phospho-NDRG1 (Thr346) Detection Kit, 50,000 Assay Points
HTRF Phospho-NDRG1 (Thr346) Detection Kit, 50,000 Assay Points
Eurofins Discoverx PathHunter Human IkB Degradation Cell-Based Assay Kit (THP-1)
The PathHunter Human IkB Degradation Stable Cell Line Assay (THP-1) measures pathway activation-induced degradation of IκB target protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human AVPR2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human AVPR2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure AVPR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0872
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0872
Eurofins Discoverx PathHunter eXpress EphB2 Functional Assay, 2-Plate Kit. (93-0848E3CP16M)
The PathHunter eXpress EphB2 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB2 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB2 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0730
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0730
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0651
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0651